Although estrogen is needed to maintain sexual health in both women and men, excessive levels of it can lead to a cluster of symptoms or even certain forms of cancer in both sexes. Instead of compounding the problem by trying to produce excessive levels of its balancing hormones progesterone or testosterone, this formula supplies Diindolylmethane (DIM) to get our bodies to produce less of the potentially harmful forms of estrogen along with a blend of antioxidants and methyl donors to help our liver's phase II detoxification pathway deal with the excess.